Embrace your sense of adventure by scaling volcanos, rafting rapids and mountain biking jungle trails. Unwind at day’s end with a relaxing massage (this is a vacation, after all).

Want to get truly off the grid? Spend quiet mornings at your secluded hotel’s spa (cellphone-free!) followed by a daily afternoon yoga class and sundowners on the beach.

Surf the Pacific and enjoy the freshest seafood imaginable before turning to your beachside cabana. When the surf drops, grab your sea kayak to explore the coast and mangrove forests.

Lose yourself in lush rainforests and jungles, zip down the longest canopy line in the world, then take to two wheels and really get off the beaten path.

Get to know the world of the Mayan people; explore their fascinating ancient ruins before cooling off in a nearby cenote. Then, it’s time for tacos (made the right way!).

This unique jungle getaway is nestled alongside the Pacuare River and best accessed by river raft. The lodge epitomizes experiential travel with fan-cooled wooden bungalows and thatched palm roofs hiding beneath giant tropical trees. Note that there is no electricity at the lodge, allowing you to experience the quiet candlelit ambiance at night and the sounds of nature right outside your door. View hotel website »

Set on over 8 km (5 mi.) of coastline, this island resort is ideal for rest and relaxation. Nestled within the palm groves, your private beachfront casita awaits—decked out with luxury amenities including indoor/outdoor showers, king-size beds and air conditioning. View hotel website »

Overlooking the Pacific Ocean and surrounded by rainforest and mangroves, the Lagarta Lodge provides the perfect base for exploring. Its intimate setting is complete with infinity pools, a spa and numerous lounges, making it the perfect place to relax after a day out. View hotel website»

Located across the bay from Portobelo, this secluded paradise offers full-time activities, private bungalows and all the beach time you could desire. The Caribbean coast is a stark contrast to the Pacific both in its feel and the wildlife you'll spot. Watch the dolphins as you sip a cocktail and start to get familiar with the Caribbean side of things. View hotel website »